On designing malaria vaccines

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Our deepening knowledge of the immune evasion mechanisms of malaria is revealing the parasite’s ability to orchestrate the human immune response. … It would thus seem futile to test novel antigens or vaccine platforms without first incorporating features designed to circumvent parasite immune evasion strategies. … The prominent feature of a successful vaccine targeting [...]...

Casares, S., & Richie, T. (2009) Immune evasion by malaria parasites: a challenge for vaccine development. Current Opinion in Immunology, 21(3), 321-330. DOI: 10.1016/j.coi.2009.05.015  Immune evasion by malaria parasites: a challenge for vaccine development


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