The origin and evolution of viruses and viral bottlenecks during multiplicity of infection

Name : Leon Matshingana
Num de plume : Mr Scientist
Title : The origin and evolution of viruses and viral bottlenecks during multiplicity of infection.
Length : 1661 words

DECLARATION I, the undersigned, declare that this essay is entirely my own written work, except where otherwise accredited.

Signed: L. Matshingana
Date: November 2016

The origin and evolution of viruses and viral bottlenecks during multiplicity of infection

Plant Genome Evolution

09/08/2013 10:50

It is our pleasure to announce the second Current Opinion Conference on Plant Genome Evolution, to be held in Amsterdam, September 8-10th, 2013. We are delighted to be holding this (now biannual) event again after a very successful first meeting in 2011 where renowned plant researchers gave inspiring talks and where many discussed their latest research in the field.

For the 2013 meeting, which will be at least half a day longer, we are even more ambitious and are trying to put together an even more exciting program focused on plant genomes, natural variation, and systems biology, of course all with a strong emphasis on evolution and evolutionary aspects.

NH Grand Hotel KrasnapolskyAmsterdam
52° 22' 8.0112" N, 4° 53' 49.7616" E
See map: Google Maps

Iternational Chromosome Conference

02/09/2013 10:42
06/09/2013 10:42

Professors Barbara Mantovani (University of Bologna), Ettore Olmo (Università Politecnica delle Marche) and Darren Griffin (University of Kent) extend a warm invitation to the Bologna to attend the 19th International Chromosome Conference (ICC). This prestigious, 49 year old, conference will focus on the many aspects of the interface research into chromosome biology nuclear organization genome evolution and post-genomic analysis.

Major topics to be presented will include:

Chromosome structure and function
Nuclear organisation and dynamics
Epigenetic and gene expression
Chromosome and genome evolution
Chromosomal aberrations in disease.
The programme will include invited talks, short talks selected from abstracts and generous time for poster presentations and networking.

We hope that you will join us for a week of high quality science and take the opportunity to meet up and network with old friends.

University of BolognaBologna
44° 29' 43.8936" N, 11° 20' 26.2932" E

Polymath goes neuro

The following is a comment I posted yesterday on Mark Changizi's "Why Doesn’t Size Matter…for The Brain?" (and more specifically, a reply to his reply to an earlier comment of mine) but which does not seem to have come through (yet?). So I am posting it here.

The corpus of science - a biophysical perspective

A month ago, Tim Jones posted the following video on his blog, featuring a montage of drawings people had made on the subject of what is important to them in science, along with their audio commentaries.

Once published, the post generated quite some interest in online communities of scientists, artists and others, and so he decided he would open up his experiment and invite others to follow, subject to a few rules. Some people have already submitted their contributions, which he has started putting together. This post is my attempt to join the party.

The Genome Sequence of Amphioxus

The genome sequence of amphioxus can be ready at:

Finally We can appreciate a conection among vertebrates and the other animals!

The Genome Sequence of Platypus

A duck? A mammal? A retile?
The Genome Sequence of platypus was published last week at Nature
The abstract can be see at:

Paper on the evolution of malaria

As we have previously discussed malaria here (see tag "Malaria"), I thought it would be of interest to take a look at the following paper:

Mideo N, Day T. On the evolution of reproductive restraint in malaria. Proc Biol Sci. 2008 Feb 26 (Epub ahead of print, http://dx.doi.org/10.1098/rspb.2007.1545 , requires subscription).

Malaria is one of the leading causes of death among infectious diseases in the world, claiming over one million lives every year. By these standards, this highly complex parasite is extremely successful at generating new infections. Somewhat surprisingly, however, many malaria species seem to invest relatively little in gametocytes, converting only a small percentage of circulating asexual parasite forms into this transmissible form. In this article, we use mathematical models to explore three of the hypotheses that have been proposed to explain this apparent ‘reproductive restraint’ and develop a novel, fourth hypothesis. We find that only one of the previous three hypotheses we explore can explain such low gametocyte conversion rates, and this hypothesis involves a very specific form of density-dependent transmission-blocking immunity. Our fourth hypothesis also provides a potential explanation and is based on the occurrence of multiple infections and the resultant within-host competition between malaria strains that this entails. Further experimental work is needed to determine which of these two hypotheses provides the most likely explanation.