acevedo

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565

Member Profile

Academic Level
Post-Doc
Position
PostDoctoral Fellow
Working Sector
Research Institute
Highest Degree
Ph. D.
Discipline
Life Sciences: Biotechnology
Reseach Topic
Synthetic biology, directed evolution, protein engineering, xenobiology
Publications

SYNTHETIC BIOLOGY AND PROTEIN ENGINEERING (*EQUAL CONTRIBUTION)

- Kille S, Acevedo-Rocha CG, et al. Reducing codon redundancy and screening effort of combinatorial protein libraries created by saturation mutagenesis. ACS SynBio. 2013; 2(2):83-92.

- Acevedo-Rocha CG*, et al. Non-canonical amino acids as a useful synthetic biological tool for lipase-catalysed reactions under hostile environments. Catal. Sci. Technol. 2013; 3:1198-1201.

- Acevedo-Rocha CG, et al. Design of protein congeners containing β-cyclopropylalanine. Molecular Biosystems 2012;8(10): 2719-23.

- Acevedo-Rocha CG and Reetz MT. Tuning lipase activity with perfluoro carboxylic acids as additives. Catal. Sci. & Technol. 2012; 2:1553-5.

- Hoesl M*, Acevedo-Rocha CG*, et al. Lipase congeners designed by genetic code engineering. ChemCatChem 2011; 3(1):213-221.

- Acevedo-Rocha CG, et al. From essential to persistent genes: A functional approach to constructing synthetic life. Trends in Genetics 2013; 2 9(5):273-9.

- Acevedo-Rocha CG and Budisa N. On the road towards chemically modified organisms endowed with a genetic firewall. Angew. Chem Int. Ed. Engl. 2011; 50(31):6960-2.

- Campeotto I and Acevedo-Rocha CG. Hijacking Nature: Novel approaches to unravel enzyme mechanisms and engineer improved biocatalysts. EMBO Rep. 2013; 14(4):299-301.

- Acevedo-Rocha CG and Palmer M. Challenges for synthetic biology. BioVision Blog 2011.

- Acevedo-Rocha CG and Reetz MT. Assembly of designed oligonucleotides: A useful tool in synthetic biology for creating high quality combinatorial DNA libraries. In: "Directed Evolution Library Creation: Methods and Protocols", Ackerley D, Copp J, & Gillam E (Eds.); Humana Press, Totowa (in press).

- Acevedo-Rocha CG, Kille S and Reetz MT. Iterative saturation mutagenesis: A powerful approach to engineer proteins by simulating Darwinian evolution. In: "Directed Evolution Library Creation: Methods and Protocols", Ackerley D, Copp J, & Gillam E (Eds.); Humana Press, Totowa (in press).

- Acevedo-Rocha CG. Genetic code engineering with methionine analogs for synthetic biotechnology. 2010 Advisor: Nediljko Budisa (Technical University Munich).

SCIENCE POLICY & COMMUNICATION

- Acevedo-Rocha CG, Yu H and Dobay A. Entgrenzung: transcending boundaries across scientific disciplines. Arkhaï 2010; (14):23-40.

- Acevedo-Rocha CG. Latin American Science: Sustainable Careers. Science 2010; 339:1274.

- Holford M, Dalton G and Acevedo-Rocha CG. Young Scientists and Social Innovators Making Science Sustainable for the Next Generation. 2013 World Science Forum: “Science for Global Sustainable Development” (report to UNESCO).

- Acevedo-Rocha CG, et al. Scientific collaboration in the changing landscape of Science: New generation of science and researchers. 2011 World Science Forum: “The Changing Landscape of Science: Challenges and opportunities” (report to UNESCO).

- Acevedo-Rocha CG. Science = art? The Euroscientist 2011;3.

- Sharp L and Acevedo-Rocha CG. New Frontiers in Science Offspring 2010; (5):13-15.

- Acevedo-Rocha CG and Steinbach J. The Art of Science and the Science of Art Offspring 2009; (4):8-13.

- Acevedo-Rocha CG. La isla del conocimiento. Ciencia 2009; 60(3):59-71.

GENOMICS & CANCER RESEARCH

- Acevedo-Rocha CG, Alvarez E, Zafra de la Rosa G, Navarro M, Gariglio P. DNA microarrays and cervical cancer: tumor marker identification. Ginecol Obstet Mex 2007; (75):205-13.

- Acevedo-Rocha CG, Munguia-Moreno JA, Ocadiz-Delgado R, Gariglio P. A transcriptome- and marker-based systematic analysis of cervical cancer. In: Topics on Cervical Cancer With an Advocacy for Prevention, Ed. Rajkumar R. InTech 2012 (ISBN: 978-953-51-0183-3).

- Acevedo-Rocha CG. Design of microarrays for the study of cervical cancer 2006; Advisors: Patricio Gariglio (CINVESTAV-IPN) and Blanca Lilia Barrón (ENCB-IPN).

Prizes / Awards

- UNESCO award, 6th World Science Forum, Rio de Janeiro, Brazil
- Burroughs Foundation grant, Research Staff Conference, Birmingham, UK
- Burroughs Foundation grant, ESOF2012, Dublin, Ireland
- UNESCO award, 5th World Science Forum, Budapest, Hungary
- ASSYST Complex Systems travel award, ECCS2011, Vienna, Austria
- Biobricks Foundation travel award, Synthetic Biology Meeting, Stanford, US
- BioVision.Nxt fellowship award, World Life Sciences Forum, Lyon, France
- Euroscience grant, European Science Open Forum (ESOF’11), Turin, Italy
- UNESCO award, 4th World Science Forum, Budapest, Hungary
- Lindau Foundation award, 56th Nobel Laureate Meeting, Lindau, Germany
- DAAD award, New Frontiers in Science Academy, Munich, Germany

Research Tags
Synthetic biology, Directed evolution, Protein engineering, Genetic code engineering, Xenobiology, Transdisciplinarity
Bio

Carlos G. Acevedo Rocha was born in Mexico-City where he studied microbiology and chemistry at the National Politechnique Institute (IPN). After his diploma thesis in oncogenomics at the research center CINVESTAV-IPN, he moved to Munich where he wrote his PhD in genetic code engineering and biocatalysis at the Max Planck Institute of Biochemistry under the guidance of Prof. Nediljko Budisa. After defending his dissertation in Summer 2010, he took a postdoctoral position related to science policy of synthetic biology in the same lab. He is member of the World Association of Young Scientists (www.ways.org) and he actively organizes interdisciplinary conferences. Since May 2011, he is postdoctoral researcher in the group of Prof. Manfred Reetz at the Faculty of Chemistry in the Phillips-Universität-Marburg. He is interested in directed and experimental evolution of proteins and cells.

General and Contact Information

Title
Dr.
First Name
Carlos G.
Last Name
Acevedo-Rocha
Languages
Spanish, English, German, French, Italian

History

Member for
7 years 25 weeks
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