World Association of Young Scientists

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Member Profile

Academic Level

PhD

Position

Research Assistant

Working Sector

Secondary School / College / University

Highest Degree

MD/MB

Discipline

Life Sciences: Immunology

Reseach Topic

Implication of cytokines and nitric oxide in immunological responses during human parasitosis (hydatidosis)

Publications

1) Mezioug D., Ait Aissa S., Amri M., Bouhadef A. & Touil-Boukoffa C. (2004). Cytokines TH1/TH2 et Monoxyde d’azote dans l’hydatidose. Journal Algérien de Médecine. 13 (2) : 66-72
2) Ait Aissa S., Amri M. & Touil-Boukoffa C. (2004). Expression de la NOS2 et Production de monoxyde d’azote au cours de l’hydatidose humaine. Sciences & Technologie, 22 : 24-31.
3) Amri M., Mezioug D., AïtAïssa S. & Touil-Boukoffa C. (2005). Purification de deux antigènes de l’échinococcose humaine par Gel Filtration et Chromatographie d’affinité. Impact sur la production de l’IL-8, l’IL-12 et le NO. Journal de la Société Algérienne de Chimie, 15 (2) : 187-194.
4) Aït Aïssa S., Amri M., Bouteldja R., Wietzerbin J. & Touil-Boukoffa C. (2006) Alteration in Interferon γ and Nitric oxide production in human echinococcosis : IFNγ and NO in anti-hydatic immune response. Cellular and Molecular Biology, 52: 65-70.
5) Amri M., Aït Aïssa S., Belguendouz H., Mezioug D. & Touil-Boukoffa C. (2007). In Vitro Antihydatic Action of Gamma Interferon (IFN-) is Dependent on Nitric Oxide (NO) pathway. Journal of Interferon & Cytokine Research, 27(9): 781-787.
6) Amri M., Mezioug D., Ait-Aissa S. & Touil-Boukoffa C. (2008). In vivo IL-12 and IL-8 production in hydatic patients and their possible diffusion in hydatid cysts. Journal of European Cytokines network, 19(3): 142-8.
7) Amri M., Mezioug D. & Touil-Boukoffa C. (2009). Involvement of IL-10 and IL-4 in evasion strategies of Echinococcus granulosus to host immune response. Journal of European Cytokines network, 20(2): 83-86.
8) Zeghir-Bouteldja R., Amri M., Ait-Aissa S., Bouaziz S., Mezioug D. & Touil-Boukoffa C. (2009). In vitro study of nitric oxide metabolites effects on human hydatid of Echinococcus granulosus. Journal of Parasitology Research, Vol 2009.
9) Rafa H., Amri M., Saoula H., Belkhelfa M., Medjeber O., Boutaleb A., Aftis A., Nakmouche M., Touil-Boukoffa C. (2010). Involvement of IFN-γ in Bowel disease Pathogenesis by Nitric Oxide Pathway: Study in Algerian Patients. Journal of Interferon & Cytokine Research, 30(9):691-7.

Prizes / Awards

1) The Algerian Award for the best publication, Algiers- Algeria, 16 April 2008.
2) The Bill and Melinda Gates health travel award to attend keystone symposia, Tahoe City- USA, 1 -5 February 2009.
3) The WAAVP AF (World Association for the Advancement of Veterinary Parasitology African Foundation) scholarship, Calgary- Canada, 8 – 13 August 2009.
4) The ISICR (International Society for Interferon and Cytokine Research- Meeting) travel award, Portugal, 18 -21 October 2009.
5) The WSPID (World Society for Pediatric Infectious Diseases) scholarship, Buenos Aires- Argentina, 19 -22 November 2009.
6) The TWAS/BVA .NXT 2010 fellowship, Alexandria,-Egypt, 10 – 15 April 2010.
7) EAACI travel grant, London- UK, 5- 9 June 2010 (Selected).
8) The Aegean conference travel award, Crete- Greece, 6 -11 June 2010 (Selected).
9) Marc Dresden Student Travel Award, Colorado Spring- USA, 22 - 25 June 2010 (Selected).
10) The ACPID travel award to attend the 5th APCID (Asian Pediatric Congress of Infectious Disease), Taipei- Taiwan, 23th- 26th September 2010.
11) The Young Scientist Forum fellowship, Melbourne- Australia, 23- 26 September 2010.
12) The APCCB (Asian-Pacific Congress of Clinical Biochemistry) travel award, Seoul- South Korea, 3- 7 October 2010 (Selected).
13) EAACI travel grant, Berlin- Germany, 21 -23 October 2010 (Selected).
14) The EFIS (European Federation of Immunological Societies) full fellowship, Sorrento- Italia, 4- 6 November 2010 (Selected).
15) The NRW stem cell network travel grant, Bonn- Germany, 6-10 December 2010.
16) The EAACI travel grant, Davos- Switzerland, 3-6 February 2011.
17) The TWAS/BVA .NXT 2011 fellowship, Lyon-France, 25- 30 March 2011.
18) EAACI travel grant, Istanbul- Turkey, 11- 15 June 2011.
19) The WAAVP AF (World Association for the Advancement of Veterinary Parasitology African Foundation) scholarship, Buenos Aires- Argentina, 21–25 August 2011.
20) LSU-WAAVP (Louisiana State University) Travel Awards, Buenos Aires- Argentina, 21–25 August 2011.
21) The 22nd World Allergy Congress travel grant, Cancun- Mexico, 4- 8 December 2011.
• We (our team) have obtained three Travel awards in ISICR Meetings (International Society for Interferon and Cytokine Research- Meeting): Seymour and Vivian Milstein Award-2005 (Shanghai- China), ISICR-2007 (UK), ISICR- 2008 (Canada).

Research Tags

Production, Action and Clinical effects of Cytokines and Nitric Oxide, hydatidosis

Bio

I’m a PhD student in the Cellular and Molecular Biology Department at the University of Sciences and Technology Houari Boumediene (USTHB), Algiers- Algeria. I received my Master degree in Biochemistry- Immunology from USTHB, Algiers. Actually, I’m a member of "Cytokines and NOSynthases" research group directed by Pr. Touil - Boukoffa C. The aim of our project is about the implication of cytokines and nitric oxide in immunological responses in infectious diseases: hydatidosis. This parasitosis constitutes a serious public health problem in various parts of the world, particularly in Algeria. Furthermore, we wished to clarify the parasite’s strategies evasion. These studies will provide useful tools for development of therapeutic strategies. Recently, we have highlighted an evident role of IFN-γ/NO in parasite killing in vitro. Moreover, IL-10 and IL-4 production seems to be an evasive mechanism taken by the parasite to establish in the host (Amri et al., 2007, 2009 & 2010).

General and Contact Information

Title

Ms.

First Name

Manel

Last Name

Amri

Country of Origin

Algeria

Country of Residence

Algeria

City

Algiers

Languages

Arabic, French, English

History

Member for

2 years 36 weeks

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